As the age progresses, soft tissue loss occurs on face. One way to replace the lost soft tissue is fillers. If the application is to be done especially in limited areas, prepared fillers are preferred because they are practical and painless and can be applied quickly in the clinic. There are a wide variety of substances in the filling materials. Some of these are permanent and some are temporary fillings. In filling applications, as well as its reliability, the efficiency of the process should be taken into account. It should be noted that what is applied is a foreign body and the use of the substances with the least risk should be taken into consideration. Among the temporary fillings, the most commonly used are fillers containing “hyaluronic acid". Retention times vary between 9 months and 12 months. Hyaluronic acid is one of the proteins that make up the connective tissue between the cells in the human body. The longer the fillings, the longer the retention time. The persistence of deep fillings can last up to 18 months. On face, It is mostly applied on the nasal-lip lines, the vertical lines between the eyebrows, the lines of sadness (Marionette) that come down from the corners of the lips and the tears in the eye. With deep fillings, cheekbones and jaw tip can be clarified. Deep fill application is done along the jaw line to create a chin contour. Thin fillings are applied to the goose feet at the sides of the eye and vertical cigarette lines on the lips. With its moisturizing feature, Pure hyaluronic acid can be applied to the whole face, lip edges, neck, décolleté and hands. With hand rejuvenation processes, the soft tissue loss on hands is removed with deep fillings and with moisturizing hyaluronic acid applications,  the quality of the skin on the back of the hand is increased.

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